Prof Ayal Hendel

Prof Ayal Hendel is a leading researcher in genome editing and gene therapy at BarIlan University in Ramat Gan, Israel. He earned his PhD from the Weizmann
Institute of Science and completed postdoctoral work at Stanford University, where he contributed to early advances in CRISPR Genome Editing.

His research focuses on developing innovative CRISPRbased strategies for targeted therapies, particularly in the realm of primary immunodeficiencies (PIDs) such as severe combined immunodeficiency (SCID). By optimising the efficiency and safety of CRISPR technologies—through approaches like chemically modified guide RNAs and precise homologydirected repair—Prof Hendel’s work aims to enable the correction of genetic defects in hematopoietic stem cells. With several influential publications, his contributions are shaping the next generation of curative gene therapies.

Learn more about his research at the Hendel Lab website.