Scientific Programme

IPIC2025 Prague – Preliminary Programme

15.00-19.00 | Registration opens

17.00-17.45 | Opening session including keynote address

Chairs: Dr Nizar Mahlaoui and Martine Pergent

  • Opening remarks – Johan Prévot & Martine Pergent
  • Keynote speech (20min): “From the immune self to immunodeficiencies” or a “philosophical conceptual framework to understand immunodeficiencies” – Prof Martin Zach

17.45-19.00 | Session 1: Use of AI tools to improve the clinical management of immunodeficiencies 

Chairs: Siobhan Burns

  • Lecture 1: An artificial intelligence Framework for Personalized Early and Timely Diagnosis and prognosis of PIDs – Dr Nicholas Rider
  • Lecture 2: AI tools for early detection of bronchiectasis
  • Lecture 3: AI to improve the genetic profiling and personalised treatment of the immunodeficient patient – Dr Maaike Kusters

19:15 | Welcome Reception 

20:30 | Industry Symposium 1 – TBC

07.30-08.30 | Industry Symposium 2 – Takeda not part of CME programme

08.00-08.30 | Guided Poster Walk 1

08.30-10.00 | Session 2: Precision Pathways: Innovating Targeted Therapies

Chairs: Prof Stuart Tangye and Prof Tadej Avcin

  • Lecture 1: JAK inhibitors in JAK/STAT IEI – Dr Carsten Speckmann
  • Lecture 2: HLH interferon gamma – Dr Fabrizio de Benedetti
  • Lecture 3: Targeted therapies used in atopic dermatitis / asthma – Prof Christine Bodemer
  • Lecture 4: Patient testimony

10.00-10.30 | Coffee Break and Guided Poster Walk 2

10.30-12.00 | Session 3: Secondary immunodeficiencies

Chairs: Dr Virgil Dalm

  • Lecture 1: When the secondary hides the primary – Prof Silvia Sanchez-Ramon
  • Lecture 2: B-cell and non B-cell targeted immunomodulation causing immunodeficiencies – Dr Sara Barmettler
  • Lecture 3: Optimal Ig therapy regimen for SID (when to start, dosage, when to stop) – Prof Stephen Jolles
  • Lecture 4: Nursing perspective on holistic treatment of the SID patients – Nurse Emily Carne

12:00-13:00 | Industry symposium 3 – Octapharma not part of CME programme

13:00-14:00 | Industry symposium 4 – Kedrion not part of CME programme

13.00-14.15 | Lunch and Poster Walk

14.15-15.45 | Session 4: Pathogen paradox – tackling complex infections in the immunodeficient patient (Case studies)

Chairs: Prof Anna Sediva and Dr Charlotte Cunningham-Rundles 

Opening: Video testimony – Igor Koruga (Serbia)

  • Lecture 1: Specific infections linked to distinct PID subcategories – Dr David Lowe
  • Lecture 2: Case study: Noro virus and Giardia parasite – Prof Surjit Singh
  • Lecture 3: Case study: Refractory mycobacterial infections in patients with IFNy antibodies – Prof Jettanong Klaewsongkram
  • Lecture 4: Case study: Fungal infection

15.45-16.15 | Coffee Break and Guided Poster Walk 3

16.15-17.30 | Session 5: Breaking topics from around the world?

Chairs: Dr Anne Barasa and Bruce Lim (10min presentations)

  • Lecture 1: Asian region – XLA HSCT vs IgRT – Prof Pamela Lee
  • Lecture 2: African region – Tunisia experience with haplo-transplantation? – Prof Monia Ouederni
  • Lecture 3: North American region – More successful commercial implementation of targeted therapies – Prof Elie Haddad
  • Lecture 4: European region – Academic/non-profit development of gene therapies – Prof Fabio Candotti
  • Lecture 5: South-American region – Newborn Screening – Prof Antonio Condino Neto

17:30-18:30 | Industry symposium 5 – Grifols not part of CME programme

20.00 | Congress Dinner

8:00-9:00 |Industry symposium 6 – Pharming not part of CME programme

9.00-10.30 | Session 6: The current status of gene therapy in  PID

Chairs: Prof Fabio Candotti

  • Lecture 1: The expanding universe of PID gene therapy (Introductory overview) – Prof Marina Cavazzana
  • Lecture 2: Can we cure genetic diseases by rewriting DNA? – Prof Ayal Hendel
  • Lecture 3: CAR T and CAR NK approaches in immune diseases – Dr Thanyavi Chinsuwan
  • Lecture 4: New avenues for gene editing / genomic medicine in PIDs (new technologies) – Prof Claire Booth

10.30-11.00 | Coffee break and Guided Poster Walk 4

11.00-12.30 | Session 7: Ethics Session: philosophical and ethical considerations to clinical boundaries in genomics

(interactive session with live-voting)

Chairs: Dr Lizzi Rivers

  • Invited Panel – Prof Alain Fischer, Prof Martin Zach, Prof James Taylor, Prof Adli Ali, Prof Rosalind Fisher, Dr Vera Frankova.

12.30-13.45 | Lunch and Poster Walk

12.30-13.30 |Industry symposium 7 – CSL not part of CME programme

13.45-14.45 |Industry symposium 8 – X4 Pharma not part of CME programme

14.45-15.15 | Young PID investigators: poster winners’ session

15.15-15.45 | Coffee break and Guided Poster Walk 5

15.45-17.00 | Session 8: “Mystic liver” – management of hepatic manifestations

Chairs: Prof Martin Van Hagen

  • Opening Lecture: The liver as essential organ in immune system – Prof Martin Van Hagen
  • Invited Panel – Prof Luc van der Laan, Dr Neil Halliday, Dr Leif Hanitsch

17.00-17.45 | Closure talk – Seeing the Whole Picture: A Comprehensive Approach to Genetic Evaluation

Chairs: Dr Nizar Mahlaoui

  • Closing Lecture – Prof Steven Holland