Scientific Programme

IPIC2025 Prague – Preliminary Programme

15.00-19.00 | Registration opens

17.00-17.45 | Opening session including keynote address

Chairs: Dr Nizar Mahlaoui and Ms Martine Pergent 

  • Opening remarks – Mr Johan Prevot  and Ms Martine Pergent
  • Keynote speech: “From the immune self to immunodeficiencies” or a “philosophical conceptual framework to understand immunodeficiencies”

17.45-19.00 | Session 1: Use of AI tools to improve the clinical management of immunodeficiencies 

  • Lecture 1: Diagnosing the undiagnosed rare disease patient with artificial intelligence
  • Lecture 2: An artificial intelligence Framework for Personalized Early and Timely Diagnosis and prognosis of PIDs
  • Lecture 3: AI to improve the genetic profiling and personalised treatment of the immunodeficient patient

19:15 | Welcome Reception 

08.00-08.30 | Guided Poster Walk

08.30-10.00 | Session 2: Precision Pathways: Innovating Targeted Therapies

  • Lecture 1: JAK inhibitors talk
  • Lecture 2: HLH interferon gamma?
  • Lecture 3: Targeted therapies used in atopic dermatitis/asthma
  • Lecture 4: Patient testimony 

10.00-10.30 | Coffee Break and Guided Poster Walk 2

10.30-12.00 | Session 3: Secondary immunodeficiencies

  • Lecture 1: When the secondary hides the primary
  • Lecture 2: B-cell and non B-cell targeted immunomodulation causing immunodeficiencies
  • Lecture 3: Optimal Ig therapy regimen for SID (when to start, dosage, when to stop)
  • Lecture 4: Nursing perspective on holistic treatment of the SID patients

13.00-14.15 | Lunch and Poster Walk

14.15-15.45 | Session 4: Pathogen paradox – tackling complex infections in the immunodeficient patient (Case studies)

Opening: Video testimony

  • Lecture 1: Specific infections linked to distinct PID subcategories
  • Lecture 2: Case study: Noro virus and Giardia parasite
  • Lecture 3: Case study: Refractory tuberculosis in patients with IFNg antibodies
  • Lecture 4: Case study: fungal infection

15.45-16.15 | Coffee Break and Guided Poster Walk 3

16.15-17.30 | Session 5: Breaking topics from around the world?

  • Lecture 1: Asian region – XLA HSCT vs IgRT? 
  • Lecture 2: African region – Tunisia experience with haplo-transplantation?
  • Lecture 3: North American region – More successful commercial implementation of targeted therapies
  • Lecture 4: European region – Academic/non-profit development of gene therapies
  • Lecture 5: South-American region – Newborn Screening

20.00 | Congress Dinner

9.00-10.30 | Session 6: The current status of gene therapy in  PID

  • Lecture 1: The expanding universe of PID gene therapy
  • Lecture 2: Can we cure genetic diseases by rewriting DNA?
  • Lecture 3: CAR T and CAR NK approaches in immune diseases
  • Lecture 4: New avenues for gene editing / genomic medicine in PIDs

10.30-11.00 | Coffee break and Guided Poster Walk 4

11.00-12.30 | Session 7: Ethics Session: philosophical and ethical considerations to clinical boundaries in genomics

12.30-13.45 | Lunch and Poster Walk

14.45-15.15 | Young PID investigators: poster winners’ session

15.15-15.45 | Coffee break and Guided Poster Walk 5

15.45-17.00 | Session 8: “Mystic liver” – management of hepatic manifestations

  • Lecture 1: The liver as essential organ in immune system
  • Lecture 2: Liver comorbidities in PIDs
  • Lecture 3: New approaches in the treatment of inflammatory liver diseases (organoids?)
  • Lecture 4: Patient testimony

17.00-17.45 | Closure talk – Seeing the Whole Picture: A Comprehensive Approach to Genetic Evaluation